Oncomine™ Lung cfDNA Assay, a comprehensive research solution designed to detect lung tumor-derived DNA (ctDNA) in cfDNA. This assay includes over 150 hotspots in 11 genes (ALK, BRAF, EGFR, ERBB2, KRAS, MAP2K1, MET, NRAS, PIK3CA, ROS1, and TP53). With our proprietary sequencing technology, a limit of detection (LOD) down to 0.1% can be achieved.
| Assay | DNA/RNA | Gene | Selected SNV hotspots | CNVs | Fusions | Extra |
| Oncomine Lung cfTNA Assay | DNA & RNA | ALK BRAF EGFR ERBB2 KRAS MAP2K1 MET NRAS PIK3CA RET ROS1 TP53 | >150 hotspots including: EGFR: T790M, C797S, L858R, Exon 19 del KRAS: G12X, G13X, Q61X BRAF: V600E ALK: Exon 21-25 PIK3CA: E545K, H1047R, E542K | MET | ALK, RET,ROS1 | MET exon 14 skipping |
