Assay | DNA/RNA | Gene | Selected SNV hotspots |
Oncomine Colon cfDNA Assay | DNA | AKT1 APC BRAF CTNNB1 EGFR ERBB2 FBXW7 GNAS KRAS MAP2K1 NRAS PIK3CA SMAD4 TP53 | >240 hotspots including:KRAS/NRAS: G12/G13/Q61 BRAF: V600EPIK3CA: E545K, H1047RTP53: R175H R273H/C/LRecurrent deleterious APC mutations (including p.R876*, p.R1114*, p.Q1378*, p.R1450*) SMAD4: R361C/H CTNNB1: S45F, T41A |